The ASAP3 Antibody (PAC038610) is a highly specific and sensitive tool for researchers studying the ASAP3 protein, a crucial player in cell signaling pathways. This polyclonal antibody, generated in rabbits, has been rigorously tested and validated for use in various applications, including Western blotting and immunofluorescence.ASAP3, also known as Arf-GAP with SH3 domain, ankyrin repeat and PH domain 3, is involved in the regulation of intracellular trafficking and signal transduction. It plays a key role in cell migration, adhesion, and cytoskeletal dynamics, making it an attractive target for studies in cell biology and cancer research.
By using the ASAP3 Antibody, researchers can accurately detect and analyze the expression levels and localization of ASAP3 in different cell types and experimental conditions. This antibody provides valuable insights into the function of ASAP3 and its potential implications in diseases such as cancer and neurological disorders. Stay ahead in your research with the reliable ASAP3 Antibody from Assay Genie.
Western blot. All lanes: ASAP3 antibody at 1µg/ml. Lane 1: A549 whole cell lysate. Lane 2: MCF-7 whole cell lysate. Lane 3: K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 100, 44, 98 kDa. Observed band size: 100 kDa.
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO38610 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO38610 at dilution of 1:100.
Background:
Promotes cell proliferation.
Synonyms:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1), ASAP3, DDEFL1 UPLC1
UniProt Protein Function:
Promotes cell proliferation.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
