The ARV1 Antibody (PAC040790) is a polyclonal antibody designed for research involving the ARV1 protein, a crucial regulator of lipid metabolism and membrane homeostasis. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in immunohistochemistry, immunofluorescence, and Western blot applications. It binds specifically to the ARV1 protein, enabling precise detection and analysis in various cell types and tissues.ARV1 plays a vital role in lipid biosynthesis and membrane integrity, making it a key player in cellular processes such as vesicle trafficking and organelle function.
Dysregulation of ARV1 has been implicated in diseases like cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its potential as a therapeutic target. Studying the function of ARV1 can provide insights into the molecular mechanisms underlying these conditions and aid in the development of targeted therapies.
Immunofluorescent analysis of A2780 cells using PACO40790 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May act as a mediator of sterol homeostasis.
Synonyms:
Protein ARV1 (hARV1), ARV1
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
this gene encodes a transmembrane protein that contains a conserved zinc ribbon motif at the N- terminus. A similar protein in mouse is thought to function in fatty acid homeostasis. Mutations in this gene are associated with early infantile epileptic encephalopathy 38. [provided by RefSeq, Nov 2016]
