The ARPC5 Polyclonal Antibody (CAB8571) is a valuable tool for researchers interested in studying the ARPC5 protein, a key component of the Arp2/3 complex involved in actin cytoskeleton regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and other applications.ARPC5 plays a crucial role in cell motility, specifically in the formation of branched actin networks that are essential for cell migration and other cellular processes. Dysregulation of ARPC5 expression has been implicated in various diseases, including cancer and neurological disorders, making it an attractive target for therapeutic interventions.
By using the ARPC5 Polyclonal Antibody, researchers can effectively detect and analyze ARPC5 protein levels in different cell types, providing valuable insights into its function and potential involvement in various physiological and pathological processes. This antibody is a powerful tool for investigations in cell biology, cancer research, and other fields where actin dynamics and cytoskeletal organization are of interest.
Product Name:
p16-ARC/ARC16/ARPC5 Rabbit Polyclonal Antibody
SKU:
CAB8571
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human p16-ARC/ARC16/p16-ARC/ARC16/ARPC5 (NP_001257368.1).
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10092
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using p16-ARC/ARC16/p16-ARC/ARC16/ARPC5 antibody (CAB8571) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
