ARPC4 Antibody (PACO18584)
- SKU:
- PACO18584
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
ARPC4 Antibody (PACO18584)
The ARPC4 Polyclonal Antibody (PAC018584) is a valuable tool for researchers studying the ARPC4 protein, a key component of the Arp2/3 complex involved in actin filament nucleation and branching. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ARPC4 plays a vital role in cytoskeletal dynamics, cell motility, and cell shape regulation, making it relevant for studies related to cell biology, cancer metastasis, and cell migration.
By targeting the ARPC4 protein, this antibody allows for the detection and analysis of ARPC4 expression in a variety of cell types, providing insights into its function and potential therapeutic applications in diseases associated with dysregulated actin dynamics. Overall, the ARPC4 Polyclonal Antibody is a valuable tool for researchers aiming to further understand the functions of ARPC4 and its implications in cellular processes and disease pathology.
| Antibody Name: | ARPC4 Antibody (PACO18584) |
| Antibody SKU: | PACO18584 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ARPC4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18584(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18584(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. |
| Synonyms: | actin related protein 2/3 complex, subunit 4, 20kDa |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010] |
| UniProt Code: | P59998 |
| NCBI GenInfo Identifier: | 311771642 |
| NCBI Gene ID: | 10093 |
| NCBI Accession: | NM_005718.4 |
| UniProt Secondary Accession: | P59998 |
| UniProt Related Accession: | P59998 |
| Molecular Weight: | |
| NCBI Full Name: | Homo sapiens actin related protein 2/3 complex subunit 4 (ARPC4), transcript variant 1, mRNA |
| NCBI Synonym Full Names: | actin related protein 2/3 complex subunit 4 |
| NCBI Official Symbol: | ARPC4Â Â |
| NCBI Official Synonym Symbols: | ARC20; P20-ARCÂ Â |
| NCBI Protein Information: | actin-related protein 2/3 complex subunit 4 |
| UniProt Protein Name: | Actin-related protein 2/3 complex subunit 4 |
| UniProt Synonym Protein Names: | Arp2/3 complex 20 kDa subunit |
| Protein Family: | Actin-related protein 2/3 complex |
| UniProt Gene Name: | ARPC4Â Â |
| UniProt Entry Name: | ARPC4_HUMAN |
| Antibodies |
| ARPC4 Antibody (PACO07862) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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