The ARPC4 Polyclonal Antibody (PAC007862) is a valuable tool for researchers studying the ARPC4 protein, a key component of the actin-related protein 2/3 complex involved in actin filament nucleation. This antibody is raised in rabbits and has high reactivity with human samples, making it suitable for Western blot applications. By binding to ARPC4, this antibody allows for the specific detection and analysis of the protein in various cell types.ARPC4 plays a crucial role in cellular processes such as cell migration, cell shape changes, and cytokinesis, making it a target of interest in cell biology and cancer research.
Understanding the function and regulation of ARPC4 is essential for unraveling its role in diseases like cancer, where dysregulation of actin dynamics can contribute to tumor progression and metastasis.The ARPC4 Polyclonal Antibody provides researchers with a reliable tool for studying the function of ARPC4 in normal and diseased cells, offering insights into the mechanisms underlying cellular processes and providing potential therapeutic targets for diseases associated with dysregulated actin dynamics.
actin related protein 2/3 complex, subunit 4, 20kDa;ARPC4;ARC20;MGC13544;p20-Arc ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]
