The ARMCX2 Antibody (PAC03698) is a polyclonal antibody designed for research involving ARMCX2, a member of the armadillo repeat-containing protein family. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for studies in molecular biology and cellular signaling pathways. ARMCX2 is known to play a role in various cellular processes, including cell proliferation and differentiation. Its specific functions in cell biology make it a valuable target for research in developmental biology, cancer biology, and neurobiology.
This antibody binds to the ARMCX2 protein, allowing for detection and analysis in a wide range of cell types and tissues.Understanding the activity of ARMCX2 is essential for unraveling its potential implications in disease states and cellular function. Research into ARMCX2 may provide insights into novel therapeutic targets for conditions such as cancer, neurological disorders, and developmental abnormalities. The ARMCX2 Antibody offers researchers a powerful tool for investigating the role of ARMCX2 in various physiological and pathological contexts.
Western blot. All lanes: ARMCX2 antibody at 5µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 66 kDa. Observed band size: 66 kDa.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO36998 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO36998 at dilution of 1:100.
Background:
May regulate the dynamics and distribution of mitochondria in neural cells.
Synonyms:
Armadillo repeat-containing X-linked protein 2 (ARM protein lost in epithelial cancers on chromosome X 2) (Protein ALEX2), ARMCX2, ALEX2 KIAA0512
UniProt Protein Function:
ARMCX2:
UniProt Protein Details:
Protein type:Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: integral to membrane
NCBI Summary:
This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
