The ARMCX2 Polyclonal Antibody (PACO15825) is a valuable tool for researchers studying the ARMCX2 protein, which is involved in various cellular processes, including mitochondrial dynamics and intracellular transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the ARMCX2 protein, researchers can investigate its role in cellular function and its potential implications in diseases such as cancer and neurodegenerative disorders.ARMCX2, a member of the armadillo repeat-containing protein family, is known to interact with proteins involved in mitochondrial fission and fusion, suggesting a role in regulating mitochondrial dynamics.
Additionally, ARMCX2 has been implicated in intracellular trafficking and may play a part in maintaining cellular homeostasis. Research into the function of ARMCX2 is essential for understanding its contribution to cellular processes and its potential as a target for therapeutic interventions.Overall, the ARMCX2 Polyclonal Antibody (PACO15825) offers researchers a reliable tool for studying the ARMCX2 protein in various research applications, providing valuable insights into its biological function and its significance in human health and disease.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15825(ARMCX2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse testis tissue, Primary antibody: PACO15825(ARMCX2 Antibody) at dilution 1/425, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15825(ARMCX2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Synonyms:
armadillo repeat containing, X-linked 2
UniProt Protein Function:
ARMCX2:
UniProt Protein Details:
Protein type:Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: integral to membrane
NCBI Summary:
This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]