The ARMCX1 Polyclonal Antibody (PAC021970) is a valuable tool for researchers studying ARMCX1, a protein involved in various cellular processes, including mitochondrial function and intracellular signaling. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ARMCX1, also known as Armadillo repeat containing X-linked protein 1, plays a crucial role in the regulation of mitochondrial dynamics and oxidative stress response. Its involvement in these pathways suggests potential implications in various diseases, such as neurodegenerative disorders and cancer.
By targeting ARMCX1, researchers can gain deeper insights into its functions and potential therapeutic applications in these disease contexts.Overall, the ARMCX1 Polyclonal Antibody is a valuable tool for researchers interested in studying mitochondrial function, intracellular signaling, and disease mechanisms related to ARMCX1. Its specificity and reliability make it an ideal choice for immunology and cancer research studies.
Antibody Name:
ARMCX1 Antibody (PACO21970)
Antibody SKU:
PACO21970
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ARMX1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from rat brain cells, using ARMX1 antibody.
Background:
Ota T., Nat. Genet. 36:40-45(2004).
Synonyms:
Armadillo repeat-containing X-linked protein 1; Protein ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; ARMCX1; ALEX1
UniProt Protein Function:
ARMCX1: Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq22.1Cellular Component: integral to membrane
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]
armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; arm protein lost in epithelial cancers, X chromosome, 1
UniProt Protein Name:
Armadillo repeat-containing X-linked protein 1
UniProt Synonym Protein Names:
ARM protein lost in epithelial cancers on chromosome X 1; Protein ALEX1