The ARL8A Antibody (PAC038934) is a high-quality polyclonal antibody specifically designed for research purposes involving ARL8A, a small GTPase protein involved in lysosomal trafficking and autophagy. This antibody, derived from rabbit hosts, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.ARL8A plays a crucial role in the regulation of lysosomal function and autophagic processes, making it a key player in cellular homeostasis and the clearance of damaged organelles. Studies have shown that dysregulation of ARL8A expression can lead to impaired autophagy and lysosomal dysfunction, contributing to the pathogenesis of diseases such as neurodegenerative disorders and cancer.
By utilizing the ARL8A Antibody, researchers can accurately detect and analyze the expression of ARL8A in various cell types, providing valuable insights into its functions and mechanisms of action in different biological contexts. This antibody is an essential tool for advancing research in areas such as cell biology, neurology, and oncology, ultimately leading to a better understanding of disease pathophysiology and the development of targeted therapeutic interventions.
Antibody Name:
ARL8A Antibody (PACO38934)
Antibody SKU:
PACO38934
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human ADP-ribosylation factor-like protein 8A protein (20-186AA)
May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation.
Synonyms:
ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2), ARL8A, ARL10B GIE2
UniProt Protein Function:
ARL8A: May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation. Belongs to the small GTPase superfamily. Arf family.Protein type: G protein, monomeric; G protein, monomeric, ARFChromosomal Location of Human Ortholog: 1q32.1Cellular Component: cytoplasm; lysosomal membrane; membrane; midbody; spindle midzoneMolecular Function: alpha-tubulin binding; beta-tubulin binding; GTP binding; protein bindingBiological Process: chromosome segregation