The ARHGAP9 Polyclonal Antibody (PACO05028) is a valuable tool for researchers studying the ARHGAP9 protein, which plays a key role in cell signaling pathways related to cytoskeletal organization and cell migration. This antibody is produced using rabbit immunoglobulins and is highly specific for detecting ARHGAP9 in human samples. Validated for use in Western blotting, it enables precise detection and quantification of ARHGAP9 protein levels in different cell types and tissues.ARHGAP9, a Rho GTPase-activating protein, is involved in the regulation of cell morphology and movement, making it essential for processes like cell migration and adhesion. Dysregulation of ARHGAP9 has been implicated in various diseases, including cancer and neurological disorders.
By studying the function of ARHGAP9, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.With its high specificity and reliability, the ARHGAP9 Polyclonal Antibody is an indispensable tool for investigating the role of ARHGAP9 in cellular processes and disease pathogenesis. Researchers in the fields of cell biology, oncology, and neurology can benefit from using this antibody to advance their understanding of ARHGAP9 function and its implications for human health.
Antibody Name:
ARHGAP9 Antibody (PACO05028)
Antibody SKU:
PACO05028
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human ARHGAP9.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ARHGAP9; Rho GTPase-activating protein 9; Rho-type GTPase-activating protein 9
UniProt Protein Function:
ARHGAP9: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; Cell adhesion; GAPs, Rac/RhoChromosomal Location of Human Ortholog: 12q13.3Cellular Component: cytosolMolecular Function: phosphatidylinositol-3,4,5-triphosphate binding; GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
