APOA1 Rabbit Polyclonal Antibody (CAB14211)
- SKU:
- CAB14211
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | APOA1 Rabbit Polyclonal Antibody |
SKU: | CAB14211 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-267 of human APOA1 (NP_000030.1). |
Sequence: | DEPP QSPW DRVK DLAT VYVD VLKD SGRD YVSQ FEGS ALGK QLNL KLLD NWDS VTST FSKL REQL GPVT QEFW DNLE KETE GLRQ EMSK DLEE VKAK VQPY LDDF QKKW QEEM ELYR QKVE PLRA ELQE GARQ KLHE LQEK LSPL GEEM RDRA RAHV DALR THLA PYSD ELRQ RLAA RLEA LKEN GGAR LAEY HAKA TEHL STLS EKAK PALE DLRQ GLLP VLES FKVS FLSA LEEY TKKL NTQ |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HPALP2; apo(a); APOA1 |
Positive Sample: | Mouse lung,mouse liver,mouse small intestine,rat lung,rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 28kDa |
Observed MW: | 31kDa |
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Purification Method: | Affinity purification |
Gene ID: | 335 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |