The UCHL1 Recombinant Rabbit Monoclonal Antibody (HDAB0204) is a powerful tool for researchers studying UCHL1, a protein involved in the regulation of cellular processes such as protein degradation and synaptic function. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human UCHL1 samples, making it suitable for Western blotting and immunohistochemistry applications.UCHL1, also known as neuronal-specific protein gene product 9.5 (PGP 9.5), is widely expressed in neurons and plays a crucial role in neurodegenerative diseases such as Parkinson's and Alzheimer's. By targeting UCHL1, researchers can gain insights into its function and potential therapeutic applications in neurology and neurodegeneration research.
With its ability to specifically bind to UCHL1, this antibody enables accurate detection and quantification of the protein in various cell types, making it an essential tool for investigations into neurological disorders and other disease states where UCHL1 regulation is implicated. Researchers can rely on this antibody to advance their understanding of UCHL1's role in health and disease, paving the way for the development of new treatments and therapies.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
