The Anti-Placental Lactogen (CSH1) Polyclonal Antibody (CAB19258) is a powerful tool for research involving the placental lactogen hormone CSH1. This antibody, raised in rabbits, is specifically designed for use in immunohistochemistry and other research applications. It is highly reactive with human samples, allowing for accurate detection and analysis of CSH1 in various tissues and cell types.CSH1 is a hormone produced by the placenta during pregnancy and plays a crucial role in regulating maternal metabolism and fetal growth. Research into CSH1 can provide valuable insights into pregnancy-related disorders, such as preeclampsia and gestational diabetes, as well as potential therapeutic targets for treating these conditions.
By utilizing the Anti-Placental Lactogen (CSH1) Polyclonal Antibody (CAB19258), researchers can further our understanding of the role of CSH1 in pregnancy and its implications for maternal and fetal health. This antibody is an essential tool for studies in reproductive biology, endocrinology, and obstetrics, offering valuable information for improving maternal and fetal outcomes.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Purification Method:
Affinity purification
Gene ID:
1442
Clone Number:
ARC2426
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human placenta using Placental lactogen (CSH1) (CSH1) Rabbit mAb (CAB19258) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
