Phospho-CGAS-S420 Rabbit Polyclonal Antibody (CABP1228)
- SKU:
- CABP1228
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- E330016A19Rik
- cGAS
Frequently bought together:
Description
Product Name: | Phospho-CGAS-S420 Rabbit Polyclonal Antibody |
SKU: | CABP1228 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic phosphorylated peptide around S420 of mouse CGAS (NP_775562.2). |
Sequence: | FCSY H |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | Mb21d1; E330016A19Rik; Phospho-CGAS-S420 |
Positive Sample: | 293T,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleoplasm, nucleus, plasma membrane |
Calculated MW: | 58kDa |
Observed MW: | 62kDa |
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 214763 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |