The MRPL37 Polyclonal Antibody (CAB4724) is a valuable tool for researchers studying mitochondrial ribosomal protein L37 (MRPL37). This antibody, raised in rabbits, is highly specific for detecting MRPL37 in human samples and is validated for use in Western blot applications. By binding to the MRPL37 protein, this antibody allows for accurate detection and analysis of MRPL37 levels in various cell types.MRPL37 is a crucial component of the mitochondrial ribosome involved in protein synthesis within the mitochondria. Dysregulation of MRPL37 has been implicated in various diseases, including cancer and metabolic disorders.
Research into the function and regulation of MRPL37 is essential for understanding its role in cellular metabolism and disease pathogenesis.The MRPL37 Polyclonal Antibody is a valuable tool for investigating the physiological and pathological functions of MRPL37 in different cellular contexts. By enabling precise detection and analysis of MRPL37 expression levels, this antibody supports research in the fields of mitochondrial biology, cancer biology, and metabolic disorders.
Antibody Name:
Anti-MRPL37 Antibody (CAB4724)
Antibody SKU:
CAB4724
Antibody Size:
50µL, 100µL
Application:
Western blotting, Immunohistochemistry
Reactivity:
Human, Mouse, Rat
Host Species:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 116-423 of human MRPL37 (NP_057575.2).
Application:
Western blotting, Immunohistochemistry
Recommended Dilution:
WB 1:200 - 1:2000 IHC 1:50 - 1:200
Reactivity:
Human, Mouse, Rat
Positive Samples:
Mouse testis, Mouse kidney, Mouse heart
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 116-423 of human MRPL37 (NP_057575.2).
Purification Method:
Affinity purification
Storage Buffer:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
