The Anti-Monomethyl Nono (R357/R365) Antibody (CAB8087) is a polyclonal antibody specifically designed for research involving the monomethylation of nono at residues 357 and 365. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blotting.Mono methylation of nono at residues 357 and 365 is known to play a role in the regulation of gene expression and cellular processes. This antibody binds specifically to the monomethylated form of nono at these specific residues, enabling accurate detection and analysis in a variety of cell types.
It is an ideal tool for researchers studying epigenetic modifications, gene regulation, and cellular signaling pathways.The Anti-Monomethyl Nono (R357/R365) Antibody (CAB8087) offers a valuable resource for researchers interested in understanding the role of nono methylation in various biological processes, and its potential implications in disease states such as cancer, neurodegenerative disorders, and developmental abnormalities. By targeting this specific modification, researchers can gain insights into the mechanisms underlying these conditions and potentially uncover novel therapeutic targets.
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
Purification Method:
Affinity purification
Gene ID:
4841
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using MonoMethyl-NONO/p54nrb-R357/R365 pAb (CAB8087) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.