The Anti-KMT1B/SUV39H2 Antibody (CAB3705) is a highly specific tool for researchers studying the KMT1B/SUV39H2 protein, which plays a key role in epigenetic regulation and gene expression. This polyclonal antibody, generated in rabbits, is able to detect KMT1B/SUV39H2 in human samples, making it ideal for use in Western blot applications.KMT1B/SUV39H2 is a histone methyltransferase that is involved in the regulation of chromatin structure and gene silencing. Dysregulation of KMT1B/SUV39H2 has been implicated in various diseases, including cancer and neurological disorders.
By targeting this protein with the CAB3705 antibody, researchers can gain valuable insights into the mechanisms by which KMT1B/SUV39H2 contributes to disease pathogenesis.Overall, the Anti-KMT1B/SUV39H2 Antibody (CAB3705) offers a powerful tool for investigating the role of KMT1B/SUV39H2 in epigenetic modifications and gene expression, paving the way for new therapeutic approaches targeting this important protein.
Product Name:
KMT1B/SUV39H2 Rabbit Monoclonal Antibody
SKU:
CAB3705
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 311-410 of human KMT1B / SUV39H2 (Q9H5I1).
Enables S-adenosyl-L-methionine binding activity; histone methyltransferase activity (H3-K9 specific); and zinc ion binding activity. Involved in chromatin assembly or disassembly and chromatin remodeling. Acts upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Located in chromatin.
Purification Method:
Affinity purification
Gene ID:
79723
Clone Number:
ARC0829
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KMT1B / SUV39H2 antibody (CAB3705) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
