The Anti-IL11RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0240) is a cutting-edge tool for researchers studying IL11RA, a cell surface receptor involved in the regulation of interleukin-11 signaling. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting IL11RA in human samples, making it a valuable asset for studies in immunology and cancer research.IL11RA, also known as interleukin-11 receptor alpha, plays a crucial role in mediating the effects of interleukin-11, a cytokine involved in various biological processes such as inflammation, hematopoiesis, and tissue regeneration. By targeting IL11RA, researchers can gain insights into the mechanisms underlying these processes, opening up new possibilities for therapeutic intervention in diseases where IL11RA signaling is dysregulated.
The Anti-IL11RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0240) offers researchers a powerful tool to explore the role of IL11RA in health and disease. Its high specificity and sensitivity, along with its validation for use in various applications such as Western blotting, make it an invaluable asset for advancing our understanding of interleukin-11 signaling pathways and developing targeted therapies for conditions where IL11RA is involved.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
