The Anti-HCoV-HKU1 Spike S1 Antibody (CAB20613) is a valuable tool for researchers studying the spike glycoprotein of the Human Coronavirus HKU1 (HCoV-HKU1). This polyclonal antibody specifically targets the spike S1 protein, which is known to play a key role in viral attachment and entry into host cells.Raised in rabbits, this antibody offers high reactivity with human samples and has been validated for use in various applications, including Western blotting and immunofluorescence. By binding to the spike S1 protein, researchers can detect and analyze its expression in different cell types, allowing for a deeper understanding of the virus-host interactions and potential therapeutic targets.
Given the ongoing global health crisis caused by the Coronavirus (COVID-19) pandemic, research into other coronaviruses, such as HCoV-HKU1, is essential for developing strategies to combat future outbreaks. The Anti-HCoV-HKU1 Spike S1 Antibody provides a valuable tool for investigating the molecular mechanisms of viral infection, aiding in the development of antiviral treatments and vaccines.
Product Name:
HCoV-HKU1 Spike S1 Rabbit Polyclonal Antibody
SKU:
CAB20613
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
HCoV-HKU1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of coronavirus Spike S1 (YP_173238.1).
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECDHis Tag)
Conjugate:
Unconjugated
Calculated MW:
152kDa
Observed MW:
75kDa/110kDa/145kDa
[Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.
Purification Method:
Affinity purification
Gene ID:
3200426
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECDHis Tag), using HCoV-HKU1 Spike S1 Rabbit pAb (CAB20613) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.