The Anti-Haspin Antibody (CAB20180) is a powerful tool for researchers studying the role of Haspin, a protein kinase involved in regulating mitotic chromosome segregation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blotting applications. By binding to the Haspin protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a valuable asset for studies in cell biology and cancer research.
Haspin is known for its crucial role in maintaining genomic stability during cell division, making it a key target for understanding diseases such as cancer, where abnormal chromosome segregation can lead to tumor formation. By investigating the function of Haspin, researchers can gain valuable insights into the mechanisms of cell cycle regulation and potentially identify new therapeutic targets for treating cancer and other related disorders.
Product Name:
HASPIN Rabbit Polyclonal Antibody
SKU:
CAB20180
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-470 of human HASPIN (NP_114171.2).
Enables ATP binding activity and histone kinase activity (H3-T3 specific). Involved in histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; intracellular signal transduction; and mitotic sister chromatid cohesion. Located in centrosome; nucleoplasm; and spindle.
Purification Method:
Affinity purification
Gene ID:
83903
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HASPIN Rabbit pAb (CAB20180) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
