The Anti-ENT2 (SLC29A2) Antibody (CAB19691) is a polyclonal antibody designed for research involving the ENT2 (SLC29A2) protein, a cell surface transporter involved in nucleoside and nucleobase transport. The antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.ENT2 (SLC29A2) plays a crucial role in nucleoside and nucleobase transport across cell membranes, which is essential for cellular processes such as DNA and RNA synthesis. Dysregulation of ENT2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for research and drug development.
The Anti-ENT2 (SLC29A2) Antibody enables researchers to detect and analyze the expression of this protein in different cell types and tissues, providing valuable insights into its role in health and disease. By understanding the function of ENT2, researchers can explore new therapeutic strategies for addressing conditions associated with nucleoside and nucleobase transport dysfunction.
Product Name:
ENT2/SLC29A2 Rabbit Monoclonal Antibody
SKU:
CAB19691
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ENT2/SLC29A2 (Q14542).
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).
Purification Method:
Affinity purification
Gene ID:
3177
Clone Number:
ARC2234
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using ENT2/SLC29A2 Rabbit mAb (CAB19691) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
