Dystrophin Rabbit Monoclonal Antibody (CAB4746)
- SKU:
- CAB4746
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BMD
- CMD3B
- DXS142
- DXS164
- DXS206
- DXS230
- DXS239
- DXS268
- DXS269
- DXS270
- DXS272
- MRX85
Frequently bought together:
Description
Product Name: | Dystrophin Rabbit Monoclonal Antibody |
SKU: | CAB4746 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532). |
Sequence: | LESQ LHRL RQLL EQPQ AEAK VNGT TVSS PSTS LQRS DSSQ PMLL RVVG SQTS DSMG EEDL LSPP QDTS TGLE EVME QLNN SFPS SRGR NTPG KPMR EDTM |
Tested Applications: | IHC-P IF/ICC ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; Dystrophin |
Conjugate: | Unconjugated |
Cellular Localization: | cell projection, cortical actin cytoskeleton, cytoskeleton, cytosol, filopodium membrane, neuron projection terminus, nucleus, plasma membrane, postsynaptic membrane, synapse, Z disc |
Calculated MW: | 427kDa |
Observed MW: | Refer to figures |
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1756 |
Clone Number: | ARC1118 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |