The Anti-CD62L Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0277) is a cutting-edge research tool designed for studying CD62L, a cell adhesion molecule involved in immune cell trafficking. This high-quality antibody, produced in rabbits, shows exceptional reactivity with human samples and has been rigorously validated for Western blot applications.CD62L, also known as L-selectin, plays a crucial role in immune cell migration and homing to lymphoid organs, making it a key player in immune response regulation. By binding specifically to CD62L, this antibody allows for precise detection and analysis of CD62L expression in various cell types.
Its reliability and specificity make it an invaluable tool for investigations in immunology, inflammation, and related fields.Researchers studying immune cell trafficking, inflammation, and immune responses will find the Anti-CD62L Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0277) to be an essential asset in their experiments. Its ability to target CD62L with high efficiency and accuracy makes it an indispensable tool for unraveling the complex mechanisms underlying immune cell dynamics and function.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
