Cadherin-13 (CDH13) Rabbit Monoclonal Antibody (CAB3244)
- SKU:
- CAB3244
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDHH
- P105
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Cadherin-13 (CDH13) Rabbit Monoclonal Antibody |
SKU: | CAB3244 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-200 of human Cadherin-13 (CDH13) (P55290). |
Sequence: | PHAE DMAE LVIV GGKD IQGS LQDI FKFA RTSP VPRQ KRSI VVSP ILIP ENQR QPFP RDVG KVVD SDRP ERSK FRLT GKGV DQEP KGIF RINE NTGS VSVT |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CDHH; P105; Cadherin-13 (CDH13) |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor |
Calculated MW: | 78kDa |
Observed MW: | 105kDa/130kDa |
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1012 |
Clone Number: | ARC1931 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |