The BOP1 Polyclonal Antibody (CAB20255) is a valuable tool for researchers studying BOP1, a protein involved in ribosome biogenesis and cell growth. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the BOP1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile option for studies in molecular biology and oncology research.
BOP1 is a key player in the production of ribosomes, the cellular machinery responsible for protein synthesis. Dysregulation of ribosome biogenesis has been implicated in various diseases, including cancer, making BOP1 a promising target for therapeutic interventions. By investigating the role of BOP1 in cellular growth and proliferation, researchers can gain insights into the mechanisms underlying disease development and potentially identify new strategies for treatment.
Product Name:
BOP1 Rabbit Polyclonal Antibody
SKU:
CAB20255
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-680 of human BOP1 (NP_056016.1).
Enables RNA binding activity. Involved in regulation of cell cycle; regulation of signal transduction by p53 class mediator; and ribosomal large subunit biogenesis. Located in chromosome; nucleolus; and nucleoplasm. Part of PeBoW complex.
Purification Method:
Affinity purification
Gene ID:
23246
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BOP1 Rabbit pAb (CAB20255) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
