AGTR1 Rabbit Monoclonal Antibody (CAB4140)
- SKU:
- CAB4140
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AG2S
- AGTR1B
- AT1
- AT1AR
- AT1B
- AT1BR
- AT1R
- AT2R1
- HAT1R
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AGTR1 Rabbit Monoclonal Antibody |
SKU: | CAB4140 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AT1R/AGTR1 (P30556). |
Sequence: | MILN SSTE DGIK RIQD DCPK AGRH NYIF VMIP TLYS IIFV VGIF GNSL VVIV IYFY MKLK TVAS VFLL NLAL ADLC FLLT LPLW AVYT AMEY RWPF GNYL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AT1; AG2S; AT1B; AT1R; ATR1; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; AT1R/AGTR1 |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | plasma membrane, Cell membrane |
Calculated MW: | 41kDa |
Observed MW: | 50kDa |
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 185 |
Clone Number: | ARC0905 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |