The ANP32C Polyclonal Antibody (PAC021686) offered by Assay Genie is a valuable tool for researchers studying ANP32C, a protein known for its involvement in various cellular processes. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the ANP32C protein, this antibody enables reliable detection and analysis in a variety of cell types, making it essential for studies in molecular biology and cell signaling.ANP32C, also referred to as acidic leucine-rich nuclear phosphoprotein 32 family member C, is a multifunctional protein that plays a role in processes such as cell proliferation, apoptosis, and RNA metabolism.
Its diverse functions make it a key target for research in fields like cancer biology, developmental biology, and neurobiology. Understanding the role of ANP32C in these processes is crucial for advancing our knowledge of cellular biology and potentially identifying new therapeutic targets. In conclusion, the ANP32C Polyclonal Antibody from Assay Genie is a reliable tool for researchers looking to explore the functions and mechanisms of ANP32C in various cellular processes. Its high reactivity, specificity, and validation make it a valuable asset for studies in molecular and cellular biology, with the potential to contribute to advancements in medical research and drug development.
Antibody Name:
ANP32C Antibody (PACO21686)
Antibody SKU:
PACO21686
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human AN32C.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells, using AN32C antibody.
Background:
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid, sequence to PP32 and are part of the same acid, c nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid, region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. Kochevar G.J., Hum. Mutat. 23:546-551(2004).
Synonyms:
acid, c leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1; ANP32C; PP32R1
UniProt Protein Function:
ANP32C: Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]Chromosomal Location of Human Ortholog: 4q32.3
UniProt Protein Details:
NCBI Summary:
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
