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Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody (CAB11013)

SKU:
CAB11013
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 2 Anti-AFP Antibody CAB11013
  • Cell Biology Antibodies 2 Anti-AFP Antibody CAB11013
  • Cell Biology Antibodies 2 Anti-AFP Antibody CAB11013
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-Fetoprotein (AFP) Rabbit Polyclonal Antibody
SKU:CAB11013
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 450-550 of Alpha-Fetoprotein (AFP) (NP_001125.1).
Sequence:ITRK MAAT AATC CQLS EDKL LACG EGAA DIII GHLC IRHE MTPV NPGV GQCC TSSY ANRR PCFS SLVV DETY VPPA FSDD KFIF HKDL CQAQ GVAL QTMK Q
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:AFPD; FETA; HPAFP; Alpha-Fetoprotein (AFP)
Positive Sample:Mouse liver
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:69kDa
Observed MW:68kDa

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Purification Method:Affinity purification
Gene ID:174
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of mouse liver, using Alpha-Fetoprotein (Alpha-Fetoprotein (AFP)) antibody (CAB11013) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.

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