ALDOB Rabbit Polyclonal Antibody (CAB3728)
- SKU:
- CAB3728
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
Product Name: | ALDOB Rabbit Polyclonal Antibody |
SKU: | CAB3728 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ALDOB (NP_000026.2). |
Sequence: | MAHR FPAL TQEQ KKEL SEIA QSIV ANGK GILA ADES VGTM GNRL QRIK VENT EENR RQFR EILF SVDS SINQ SIGG VILF HETL YQKD SQGK LFRN ILKE KGIV VGIK LDQG GAPL AGTN KETT IQGL DGLS ERCA QYKK DGVD FGKW RAVL RIAD QCPS SLAI QENA NALA RYAS ICQQ NGLV PIVE PEVI PDGD HDLE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | ALDB; ALDO2; ALDOB |
Positive Sample: | Mouse liver,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centriolar satellite, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 39kDa |
Observed MW: | 40kDa |
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Purification Method: | Affinity purification |
Gene ID: | 229 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |