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AKR7A3 Monoclonal Antibody [PAT2E11] (CPAB0114)

SKU:
CPAB0114
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT2E11
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

AKR7A3 Monoclonal Antibody [PAT2E11] (CPAB0114)

The AKR7A3 Polyclonal Antibody (CPAB0114) is a specialized research tool for studying AKR7A3, an important enzyme involved in detoxification processes and drug metabolism. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications.AKR7A3, a member of the aldo-keto reductase superfamily, plays a crucial role in the metabolism of a wide range of endogenous and exogenous compounds, including drugs, carcinogens, and environmental toxins. By targeting AKR7A3, researchers can gain insights into the mechanisms of detoxification and drug metabolism, facilitating studies in toxicology, pharmacology, and drug development.

The AKR7A3 Polyclonal Antibody enables the detection and analysis of AKR7A3 protein levels in various cell types, providing valuable information for investigating the role of this enzyme in health and disease. Its application in research on drug metabolism, chemical detoxification, and xenobiotic metabolism makes it an essential tool for advancing our understanding of metabolic processes and developing novel therapeutic strategies.

Product Name:AKR7A3 Antibody
Product Sku:CPAB0114
Size:5μg
Host Species:Mouse
Immunogen:Anti-human AKR7A3, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human AKR7A3 amino acids 1-331 purified from Ecoli.
Clone:PAT2E11.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:AKR7A3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:AKR7A3, takes part in the detoxification of aldehydes and ketones. AKR7A3 reduces the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. AKR7A3 participates in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Synonyms:AFAR2, Aflatoxin B1 aldehyde reductase member 3, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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