The AKAP3 Polyclonal Antibody (CAB16484) is a valuable tool for researchers studying AKAP3, a protein known to play a role in sperm motility and male fertility. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.AKAP3, also known as A-kinase anchor protein 3, is involved in compartmentalizing signaling molecules in sperm cells, aiding in the regulation of sperm movement and function. Research on AKAP3 is crucial for understanding male infertility and developing potential therapies to address this issue.
By utilizing the AKAP3 Polyclonal Antibody, researchers can detect and analyze AKAP3 protein levels in different cell types, providing valuable insights into its function and potential implications in reproductive health. This antibody is a valuable tool for studies in reproductive biology and may lead to advancements in fertility treatments and male reproductive health.
Product Name:
AKAP3 Rabbit Polyclonal Antibody
SKU:
CAB16484
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AKAP3 (NP_006413.3).
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction.
Purification Method:
Affinity purification
Gene ID:
10566
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat testis, using AKAP3 Rabbit pAb (CAB16484) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
