The AGFG2 Polyclonal Antibody (PACO07641) is a valuable tool for researchers studying AGFG2, a protein involved in multiple cellular processes, including intracellular trafficking and membrane fusion. This antibody is produced in rabbits and has been validated for use in various applications, with a high level of reactivity in human samples.AGFG2, also known as Arf-GAP with FG repeats 2, is a key player in regulating vesicle-mediated transport within cells. By binding to AGFG2, researchers can investigate its role in cellular pathways related to protein sorting, membrane remodeling, and organelle dynamics.
This antibody is particularly useful for studies in cell biology, molecular biology, and drug discovery.The functionality of AGFG2 in cellular processes makes it a promising target for research into diseases like cancer, neurodegenerative disorders, and infectious diseases. By understanding the mechanisms by which AGFG2 functions, researchers can potentially develop novel therapeutic strategies to target these conditions. The AGFG2 Polyclonal Antibody is a reliable tool for enabling such investigations and expanding our understanding of AGFG2 biology.
HRBL: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q22.1Cellular Component: membrane
UniProt Protein Details:
NCBI Summary:
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013]
