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Low Endotoxin Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL1469)

SKU:
AGEL1469
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$227 - $1,115
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Description

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Low Endotoxin Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The AF-Le Purified Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (RB6-8C5) is a highly specific and reliable tool for detecting and studying LY-6G/LY-6C (Gr-1) proteins in biological samples. This monoclonal antibody, produced by AssayGenie, is purified from mouse ascites fluid and has been extensively validated for various applications in research.LY-6G/LY-6C (Gr-1) is a marker commonly used to identify and characterize granulocytes and monocytes in murine systems. These cells play crucial roles in inflammation, immune responses, and disease pathogenesis. The RB6-8C5 antibody binds specifically to the LY-6G/LY-6C (Gr-1) proteins, enabling accurate detection and analysis of these cell populations in experimental settings.

Researchers in the fields of immunology, cancer biology, and inflammatory diseases will find this antibody particularly valuable for investigating the roles of granulocytes and monocytes in various physiological and pathological processes. Its high specificity and reliability make it an essential tool for flow cytometry, immunofluorescence, and other molecular biology techniques aimed at understanding the complex functions of LY-6G/LY-6C (Gr-1) cells.By utilizing the AF-Le Purified Mouse LY-6G/LY-6C (Gr-1) Monoclonal Antibody (RB6-8C5) in their studies, scientists can advance our knowledge of immune cell biology and potentially uncover novel therapeutic targets for diseases involving dysregulated immune responses.

Product Title:Low Endotoxin Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL1469
Size:50µg, 500µg, 1mg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM;Depletion
Isotype:Rat IgG2b, κ
Isotype Control:AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.1 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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