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Low Endotoxin Purified Anti-Human CD8a Antibody [OKT-8] (AGEL1390)

SKU:
AGEL1390
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€189 - €929
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human CD8a Antibody [OKT-8]

The CD8A Monoclonal Antibody (OKT-8) from Assay Genie is a high-quality tool for research involving the CD8A cell surface antigen. This purified human monoclonal antibody is specifically designed for use in immunology and cell biology studies, particularly in the analysis of T cell populations.CD8A, also known as the T-cell co-receptor, plays a crucial role in immune responses by recognizing antigens presented on major histocompatibility complex (MHC) class I molecules. The OKT-8 antibody, validated for use in various applications such as flow cytometry and immunohistochemistry, allows for the precise detection and characterization of CD8A-positive T cells in human samples.Researchers investigating immune responses, infectious diseases, autoimmune disorders, and cancer biology can benefit from the specific reactivity and reliability of the CD8A Monoclonal Antibody (OKT-8).

Its ability to target and detect the CD8A protein in different cell types makes it a valuable asset in a wide range of experimental settings, providing insights into immune cell function and interactions.For accurate and reproducible results in studies exploring T cell biology and immune system function, the CD8A Monoclonal Antibody (OKT-8) from Assay Genie offers a powerful tool with exceptional specificity and sensitivity. Unlock the potential of your research with this reliable antibody for CD8A detection and analysis.

Product Title:Low Endotoxin Purified Anti-Human CD8a Antibody [OKT-8]
SKU:AGEL1390
Size:50µg, 500µg, 1mg
Clone No:OKT-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM;Depletion
Isotype:Mouse IgG2a, κ
Isotype Control:AF/LE Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01732
Gene ID:925
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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