The Anti-Human HLA-A, B, C Antibody W6/32 (AG2021) is a purified monoclonal antibody designed for research involving the human leukocyte antigen (HLA) system. This antibody, derived from mouse hybridoma cells, specifically targets and binds to HLA-A, B, and C antigens on human cells, enabling accurate detection and analysis in various research applications.The HLA-A, B, C antigens are crucial components of the immune system, playing a key role in immune response regulation and the presentation of antigens to T cells. The W6/32 antibody is highly specific to these HLA antigens, making it an essential tool for studies focused on immune recognition, transplantation biology, infectious diseases, and autoimmune disorders.
With its high reactivity and specificity to human HLA-A, B, and C antigens, the Anti-Human HLA-A, B, C Antibody W6/32 (AG2021) is a valuable asset for researchers in immunology, transplant biology, and related fields. Its ability to precisely target and detect HLA antigens opens up new avenues for understanding immune responses and developing targeted therapies for various diseases and conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P04439 P01889 P10321
Gene ID:
3105
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.