The ADCK5 Antibody (PAC021870) is a powerful tool for researchers studying the ADCK5 protein, which is involved in various cellular processes including mitochondrial function and signaling pathways. This antibody is polyclonal, raised in rabbits, and is highly specific for human samples. Validated for use in Western blot applications, it allows for the detection and analysis of ADCK5 in a variety of cell types.ADCK5, also known as a putative kinase, is a key player in mitochondrial function and energy production. Dysregulation of ADCK5 has been linked to various diseases such as Parkinson's disease, making it an important target for therapeutic research.
By understanding the role of ADCK5 in cellular function, researchers can uncover new insights into disease mechanisms and potential treatment options.Overall, the ADCK5 Antibody offers researchers a reliable tool for studying the function and regulation of the ADCK5 protein in both normal and diseased states, leading to advancements in our understanding of mitochondrial biology and potential therapeutic interventions.
Antibody Name:
ADCK5 Antibody (PACO21870)
Antibody SKU:
PACO21870
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ADCK5.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, 293 cells and HUVEC cells, using ADCK5 antibody.
Background:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). The MGC Project Team, Genome Res. 14:2121-2127(2004)
Synonyms:
Uncharacterized aarF domain-containing protein kinase 5; EC 2.7.11; ADCK5;
UniProt Protein Function:
ADCK5: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). Belongs to the protein kinase superfamily. ADCK protein kinase family.
UniProt Protein Details:
Protein type:Kinase, protein; EC 2.7.11.-; Protein kinase, Ser/Thr (non-receptor); EC 2.7.-.-; Protein kinase, atypical; Membrane protein, integral; ATYPICAL group; ABC1 family; ABC1-B subfamily