ADAMTS2 Rabbit Polyclonal Antibody (CAB10272)
- SKU:
- CAB10272
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ADAMTS2 Rabbit Polyclonal Antibody |
SKU: | CAB10272 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1029-1213 of human ADAMTS2 (O95450). |
Sequence: | PRNI SDPS KKSY VVQW LSRP DPDS PIRK ISSK GHCQ GDKS IFCR MEVL SRYC SIPG YNKL CCKS CNLY NNLT NVEG RIEP PPGK HNDI DVFM PTLP VPTV AMEV RPSP STPL EVPL NASS TNAT EDHP ETNA VDEP YKIH GLED EVQP PNLI PRRP SPYE KTRN QRIQ ELID EMRK KEML GKF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS; ADAMTS2 |
Positive Sample: | A375,U-87MG,THP-1,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 135kDa |
Observed MW: | 120kDa |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 9509 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |