The ADAMTS1 Monoclonal Antibody is a powerful tool for researchers studying ADAMTS1, an enzyme involved in extracellular matrix degradation and tissue remodeling. This antibody, produced in a monoclonal format, offers high specificity and sensitivity for detecting ADAMTS1 in various biological samples, making it ideal for use in immunohistochemistry and immunofluorescence applications.ADAMTS1 plays a key role in processes such as angiogenesis, wound healing, and inflammation, making it a potential target for therapeutic intervention in conditions such as cancer and arthritis.
By using the ADAMTS1 Monoclonal Antibody, researchers can gain valuable insights into the expression and activity of this enzyme in different biological contexts, ultimately advancing our understanding of its role in health and disease.Overall, the ADAMTS1 Monoclonal Antibody is a valuable tool for investigating the function of ADAMTS1 in various biological processes, offering researchers the means to explore new avenues for therapeutic development and precision medicine.
Product Name:
ADAMTS1 Monoclonal Antibody
SKU:
CAB23840
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequen cecorresponding to amino acids 50-174 of human ADAMTS1(NP_008919.3).
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
Purification Method:
Affinity purification
Gene ID:
9510
Clone Number:
ARC61847
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of 293F cells using ADAMTS1 Rabbit mAb (CAB23840) at a dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
