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ACOT12 Antibody (PACO23374)

SKU:
PACO23374
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • ACOT12 Antibody PACO23374
  • ACOT12 Antibody PACO23374
€419
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Description

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ACOT12 Antibody (PACO23374)

The ACOT12 Polyclonal Antibody (PAC023374) is a valuable tool for researchers interested in studying ACOT12, a protein involved in lipid metabolism and fatty acid oxidation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ACOT12 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in metabolism and related diseases.ACOT12, also known as acyl-coenzyme A thioesterase 12, plays a crucial role in lipid metabolism by catalyzing the hydrolysis of acyl-CoAs to free fatty acids and CoA-SH.

Dysregulation of ACOT12 has been linked to metabolic disorders, fatty liver disease, and obesity. Understanding the function of ACOT12 can provide insights into these diseases and potentially lead to the development of targeted therapies.Overall, the ACOT12 Polyclonal Antibody is a valuable tool for researchers investigating lipid metabolism, fatty acid oxidation, and related diseases. Its high reactivity and specificity make it an essential component of any study involving ACOT12 expression and function.

Antibody Name:ACOT12 Antibody (PACO23374)
Antibody SKU:PACO23374
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500
Species Reactivity:Human, Mouse
Immunogen:Synthesized peptide derived from internal of human ACOT12.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ACOT12 antibody.
Product ImageImmunofluorescence analysis of A549 cells, using ACOT12 antibody.
Background:Hydrolyzes acetyl-CoA to acetate and CoA.
Synonyms:Acyl-coenzyme A thioesterase 12; EC 3.1.2.1; Acyl-CoA thioesterase 12; Acyl-CoA thioester hydrolase 12; Cytoplasmic acetyl-CoA hydrolase 1
UniProt Protein Function:ACOT12: Hydrolyzes acetyl-CoA to acetate and CoA.Protein type: Carbohydrate Metabolism - pyruvate; Hydrolase; EC 3.1.2.1Chromosomal Location of Human Ortholog: 5q14.1Cellular Component: cytosolMolecular Function: acetyl-CoA hydrolase activity; lipid binding; ATP bindingBiological Process: acyl-CoA metabolic process; acetyl-CoA metabolic process; fatty acid metabolic process; pyruvate metabolic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WYK0
NCBI GenInfo Identifier:18640736
NCBI Gene ID:134526
NCBI Accession:NP_570123
UniProt Secondary Accession:Q8WYK0,Q5FWE9, B3KVK9
UniProt Related Accession:Q8WYK0
Molecular Weight:18,327 Da
NCBI Full Name:acyl-coenzyme A thioesterase 12
NCBI Synonym Full Names:acyl-CoA thioesterase 12
NCBI Official Symbol:ACOT12  
NCBI Official Synonym Symbols:Cach; THEAL; CACH-1; STARD15  
NCBI Protein Information:acyl-coenzyme A thioesterase 12
UniProt Protein Name:Acyl-coenzyme A thioesterase 12
UniProt Synonym Protein Names:Acyl-CoA thioester hydrolase 12; Cytoplasmic acetyl-CoA hydrolase 1; CACH-1; hCACH-1; START domain-containing protein 15; StARD15
Protein Family:Acyl-coenzyme A thioesterase
UniProt Gene Name:ACOT12  
UniProt Entry Name:ACO12_HUMAN
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