The ACADM Rabbit Monoclonal Antibody (CAB4567) is a valuable tool for research involving ACADM, an enzyme involved in fatty acid metabolism and energy production in cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the ACADM protein, enabling accurate detection and analysis in a variety of cell types.ACADM plays a crucial role in breaking down fatty acids to produce energy, making it a key player in metabolic processes.
Dysregulation of ACADM has been linked to metabolic disorders and diseases such as fatty acid oxidation disorders. Studying the function and regulation of ACADM is essential for understanding these conditions and developing potential therapeutic interventions. Overall, the ACADM Rabbit Monoclonal Antibody (CAB4567) serves as a reliable tool for researchers in the fields of metabolism, energy production, and metabolic disorders, enabling precise detection and analysis of ACADM in various biological samples.
Product Name:
ACADM Rabbit Monoclonal Antibody
SKU:
CAB4567
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ACADM (P11310).
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
34
Clone Number:
ARC1035
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACADM Rabbit mAb (CAB4567) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
