ABHD12 Rabbit Polyclonal Antibody (CAB17678)
- SKU:
- CAB17678
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ABHD12 Rabbit Polyclonal Antibody |
SKU: | CAB17678 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human ABHD12 (NP_056415.1). |
Sequence: | YFID LKKP QDQG LNHT CNYY LQPE EDVT IGVW HTVP AVWW KNAQ GKDQ MWYE DALA SSHP IILY LHGN AGTR GGDH RVEL YKVL SSLG YHVV TFDY RGWG DSVG TPSE RGMT YDAL HVFD WIKA RSGD NPVY IWGH SLGT G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PHARC; ABHD12A; BEM46L2; hABHD12; C20orf22; dJ965G21.2; ABHD12 |
Positive Sample: | Rat brain,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | dendrite cytoplasm, plasma membrane |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 26090 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |