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ABCC12 Antibody (PACO00354)

SKU:
PACO00354
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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ABCC12 Antibody (PACO00354)

The ABCC12 Polyclonal Antibody (PACO00354) is a valuable tool for researchers studying the ABCC12 gene, a member of the ATP-binding cassette (ABC) transporter family. This antibody is raised in rabbits and shows high specificity and reactivity with human samples, making it suitable for a range of research applications.ABCC12 is known to be involved in multidrug resistance and the transportation of various molecules across cell membranes. Its overexpression has been linked to drug resistance in cancer cells, making it a potential target for cancer therapy research.

The ABCC12 Polyclonal Antibody binds specifically to the ABCC12 protein, allowing for detection and analysis in different cell types and tissues.By using the ABCC12 Polyclonal Antibody in experiments, researchers can gain valuable insights into the role of ABCC12 in drug resistance, transport mechanisms, and potential therapeutic targets. This antibody is validated for use in Western blot applications and is a valuable tool for studies in cancer biology, pharmacology, and drug development.

Antibody Name:ABCC12 Antibody
Antibody SKU:PACO00354
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human
Immunogen:synthesized peptide derived from the Internal region of human ABCC12.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12
UniProt Protein Function:ABCC12: Probable transporter. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 16q12.1

NCBI Summary:This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
UniProt Code:Q96J65
NCBI GenInfo Identifier:161788999
NCBI Gene ID:94160
NCBI Accession:Q96J65.2
UniProt Secondary Accession:Q96J65,Q49AL2, Q8TAF0, Q8TEY2,
UniProt Related Accession:Q96J65
Molecular Weight:104,660 Da
NCBI Full Name:Multidrug resistance-associated protein 9
NCBI Synonym Full Names:ATP binding cassette subfamily C member 12
NCBI Official Symbol:ABCC12  
NCBI Official Synonym Symbols:MRP9  
NCBI Protein Information:multidrug resistance-associated protein 9
UniProt Protein Name:Multidrug resistance-associated protein 9
UniProt Synonym Protein Names:ATP-binding cassette sub-family C member 12
Protein Family:ABC transporter C family
UniProt Gene Name:ABCC12  
UniProt Entry Name:MRP9_HUMAN

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