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ABCB9 Antibody (PACO07521)

SKU:
PACO07521
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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ABCB9 Antibody (PACO07521)

The ABCB9 Polyclonal Antibody (PACO7521) is a valuable tool for researchers studying ABCB9, a protein involved in cellular transport and multidrug resistance. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blot analysis. By binding to the ABCB9 protein, this antibody enables the detection and analysis of ABCB9 in different cell types, making it a valuable resource for studies in molecular biology and pharmacology.ABCB9, also known as ATP-binding cassette sub-family B member 9, plays a crucial role in the transport of molecules across cell membranes and is associated with resistance to multiple drugs.

Understanding the function and regulation of ABCB9 is important for developing strategies to overcome drug resistance and improve the effectiveness of cancer treatments. This antibody provides researchers with a reliable tool to study ABCB9 and its impact on drug resistance mechanisms, making it an essential component of research in oncology and pharmacology.

Antibody Name:ABCB9 Antibody (PACO07521)
Antibody SKU:PACO07521
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human ABCB9
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ATP-binding cassette, sub-family B (MDR/TAP), member 9;ABCB9;EST122234;KIAA1520;TAPL ;
UniProt Protein Function:ABCB9: ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 12q24Cellular Component: lysosomal membrane; lysosome; endoplasmic reticulum; early endosome; integral to membrane; integral to endoplasmic reticulum membraneMolecular Function: protein binding; protein homodimerization activity; substrate-specific transmembrane transporter activity; ATP binding; peptide-transporting ATPase activityBiological Process: peptide transport; antigen processing and presentation of peptide antigen via MHC class I; protein transport; metabolic process; transmembrane transport
UniProt Protein Details:
NCBI Summary:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]
UniProt Code:Q9NP78
NCBI GenInfo Identifier:22095458
NCBI Gene ID:23457
NCBI Accession:Q9NP78.1
UniProt Secondary Accession:Q9NP78
UniProt Related Accession:Q9NP78
Molecular Weight:84kDa
NCBI Full Name:ATP-binding cassette sub-family B member 9
NCBI Synonym Full Names:ATP binding cassette subfamily B member 9
NCBI Official Symbol:ABCB9  
NCBI Official Synonym Symbols:TAPL; EST122234  
NCBI Protein Information:ATP-binding cassette sub-family B member 9
UniProt Protein Name:ATP-binding cassette sub-family B member 9
UniProt Synonym Protein Names:ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL
Protein Family:ABC transporter B family
UniProt Gene Name:ABCB9  
UniProt Entry Name:ABCB9_HUMAN

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