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ABCA13 Antibody (PACO22167)

SKU:
PACO22167
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$503
Frequently bought together:

Description

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ABCA13 Antibody (PACO22167)

The ABCA13 Polyclonal Antibody (PAC022167) is a valuable tool for researchers studying the ATP-binding cassette transporter 13 (ABCA13) protein. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ABCA13 protein, researchers can accurately detect and analyze this transporter in various cell types.ABCA13 is a member of the ATP-binding cassette transporter family, which plays a crucial role in cellular lipid transport and homeostasis. Dysregulation of ABCA13 has been implicated in various diseases, including neurodegenerative disorders and cancer.

By investigating the function of ABCA13 using the PAC022167 antibody, researchers can gain insights into its role in health and disease.This antibody is a valuable tool for studies in molecular biology, cell biology, and biochemistry, providing researchers with the ability to examine the expression and function of ABCA13 in different biological contexts. With its high specificity and sensitivity, the PAC022167 antibody is an essential asset for advancing research in the field of transporter biology.

Antibody Name:ABCA13 Antibody (PACO22167)
Antibody SKU:PACO22167
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IF:1:100-1:500
Species Reactivity:Human
Immunogen:Synthesized peptide derived from internal of human ABCA13.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunofluorescence analysis of A549 cells, using ABCA13 antibody.
Background:In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.
Synonyms:ATP-binding cassette sub-family A member 13;
UniProt Protein Function:ABCA13: In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7p12.3Cellular Component: integral to membraneMolecular Function: transporter activity; ATPase activity; ATP bindingBiological Process: transport; metabolic process
UniProt Protein Details:
NCBI Summary:In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]
UniProt Code:Q86UQ4
NCBI GenInfo Identifier:597709765
NCBI Gene ID:154664
NCBI Accession:NP_689914.3
UniProt Secondary Accession:Q86UQ4,Q6ZTT7, Q86WI2, Q8N248, K9LC76, K9LC79, K9LCX7 K9LDK8, K9LDY4
UniProt Related Accession:Q86UQ4
Molecular Weight:258,321 Da
NCBI Full Name:ATP-binding cassette sub-family A member 13
NCBI Synonym Full Names:ATP-binding cassette, sub-family A (ABC1), member 13
NCBI Official Symbol:ABCA13  
NCBI Official Synonym Symbols:
NCBI Protein Information:ATP-binding cassette sub-family A member 13; ATP binding cassette transporter A13; ATP-binding cassette sub-family A member 13 variant 2; ATP-binding cassette sub-family A member 13 variant 3
UniProt Protein Name:ATP-binding cassette sub-family A member 13
UniProt Synonym Protein Names:
Protein Family:ATP-binding cassette sub-family
UniProt Gene Name:ABCA13  
UniProt Entry Name:ABCAD_HUMAN
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