The TSPAN8 Polyclonal Antibody (CAB13267) is a valuable tool for researchers studying TSPAN8, a cell surface protein known to be involved in tumor progression and metastasis. This antibody, derived from rabbit serum, is highly specific to human TSPAN8 and has been validated for use in various applications including Western blot and immunohistochemistry.TSPAN8, a member of the tetraspanin family, is known to interact with integrins and other cell surface molecules to regulate cell migration, invasion, and adhesion.
Its expression has been detected in various cancer types, making it a potential target for cancer therapy and diagnostic biomarkers.By utilizing the TSPAN8 Polyclonal Antibody, researchers can explore the role of TSPAN8 in cancer biology, potentially leading to the development of novel targeted therapies and diagnostic tools. Its high specificity and sensitivity make it an essential tool for studies in oncology and cancer research.
Product Name:
TSPAN8 Rabbit Polyclonal Antibody
SKU:
CAB13267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human TSPAN8 (NP_004607.1).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7103
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of A-549, using TSPAN8 antibody (CAB13267) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
