The POP5 Polyclonal Antibody (CAB16530) is a valuable tool for researchers studying POP5, a protein involved in RNA processing and ribosome biogenesis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards POP5 in human samples, making it suitable for Western blot applications. By recognizing and binding to the POP5 protein, this antibody enables the accurate detection and analysis of POP5 expression in various cell types.POP5 is a crucial component of the RNase MRP complex, which plays a vital role in the cleavage of RNA molecules and the maturation of ribosomal RNA.
Dysregulation of POP5 has been linked to various diseases, including cancers and genetic disorders. Therefore, elucidating the functions and mechanisms of POP5 is essential for understanding its impact on cellular processes and disease development.By using the POP5 Polyclonal Antibody, researchers can further investigate the function of POP5 and its potential role in disease pathogenesis. This antibody serves as a valuable tool for studies in molecular biology, RNA biology, and cancer research, providing insights into the mechanisms underlying RNA processing and ribosome biogenesis.
Product Name:
POP5 Rabbit Polyclonal Antibody
SKU:
CAB16530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human POP5 (NP_057002.2).
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in nucleolus. Part of multimeric ribonuclease P complex and ribonuclease MRP complex.
Purification Method:
Affinity purification
Gene ID:
51367
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using POP5 Rabbit pAb (CAB16530) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
