The POC1A Polyclonal Antibody (CAB7465) is a high-quality research tool specifically designed for the detection and analysis of the POC1A protein. POC1A is a protein involved in centriole biogenesis and cell cycle regulation, making it a key target for studies in cell biology and cancer research.Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the POC1A protein, researchers can accurately and efficiently study its function in various cell types.
This antibody is ideal for immunology and cancer research, where understanding the role of POC1A can provide valuable insights into cellular processes and potential therapeutic targets.With its ability to enable the detection and analysis of POC1A, the CAB7465 Polyclonal Antibody is essential for advancing our knowledge of cellular biology and disease mechanisms. Researchers can rely on its specificity and reliability to drive important discoveries in the fields of cell cycle regulation and cancer biology.
Product Name:
POC1A Rabbit Polyclonal Antibody
SKU:
CAB7465
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 138-407 of human POC1A (NP_056241.3).
Cytoplasm, centriole, centrosome, cilium basal body, cytoskeleton, microtubule organizing center, spindle pole.
Calculated MW:
45kDa
Observed MW:
45kDa
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.
Purification Method:
Affinity purification
Gene ID:
25886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POC1A antibody (CAB7465) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
