The PerCP-Cyanine5.5 Anti-Mouse/Human CD11b Antibody (M1/70) offered by Assay Genie is a valuable tool for researchers studying immune cell populations in both mice and humans. This antibody, conjugated with PerCP-Cyanine5.5, specifically targets CD11b, a cell surface protein commonly found on myeloid cells.CD11b, also known as integrin alpha-M, is a crucial marker for identifying and studying monocytes, macrophages, and granulocytes. By utilizing this antibody, researchers can easily detect and analyze the expression of CD11b in various cell types using flow cytometry or fluorescence microscopy techniques.
The M1/70 Antibody is highly specific and reliable, ensuring accurate results in your experimental studies. It is suitable for a wide range of applications, including immunophenotyping, cell sorting, and investigating the role of CD11b-expressing cells in immune responses, inflammation, and disease pathology.With its proven effectiveness in detecting CD11b in both mouse and human samples, the PerCP-Cyanine5.5 Anti-Mouse/Human CD11b Antibody (M1/70) from Assay Genie is an essential reagent for researchers in the fields of immunology, inflammation, and cancer research.
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:
Rat
Reactivity:
Human;Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05555 P11215
Gene ID:
16409,3684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.