The PerCP-Cyanine5.5 Anti-Mouse CD5 Antibody (53-7.3) is a valuable tool for researchers studying mouse CD5, a cell surface marker expressed on T cells and B-1a cells. This monoclonal antibody, clone 53-7.3, is specifically designed for flow cytometry applications, enabling precise identification and analysis of CD5-positive cells in mouse samples.CD5, a lymphocyte cell surface glycoprotein, is involved in regulating immune responses and is considered a marker for T cells and B-1a cells. Its expression pattern and function in the immune system make it a key molecule for understanding immune cell development, activation, and tolerance mechanisms.
The PerCP-Cyanine5.5 Anti-Mouse CD5 Antibody (53-7.3) offers high specificity and sensitivity in detecting mouse CD5, making it an excellent tool for immunology research, including studies on T cell and B-1a cell subsets, immune responses, and autoimmune diseases. With this antibody, researchers can explore the role of CD5 in immune cell function and its potential as a therapeutic target in immunological disorders and cancer immunotherapy.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL3276
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.