PAICS Rabbit Polyclonal Antibody (CAB6450)
- SKU:
- CAB6450
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PAICS Rabbit Polyclonal Antibody |
SKU: | CAB6450 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS (NP_001072992.1). |
Sequence: | LEKS WLPQ NCTL VDMK IEFG VDVT TKEI VLAD VIDN DSWR LWPS GDRS QQKD KQSY RDLK EVTP EGLQ MVKK NFEW VAER VELL LKSE SQCR VVVL MGST SDLG HCEK IKKA CGNF GIPC ELRV TSAH KGPD ETLR IKAE YEGD GIPT VFVA VAGR SNGL GPVM SGNT AYPV ISCP PLTP DWGV QDVW SSLR LPSG LGCS TVLS PEGS AQFA AQIF GLSN HLVW SKLR ASIL NTWI SLKQ ADKK IREC NL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | ADE2; AIRC; PAIS; ADE2H1; PAICSD; PAICS |
Positive Sample: | Jurkat,293T,SW620,Raji,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10606 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |